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ALL MY PATIENTS HAVE TALES CITY OF PUBLICATION TRIAL

Hispanic patients with severe hemophilia are about twice as likely to get an inhibitor than non-Hispanic white patients.A recent study of young children with bleeding disorders found evidence for decreasing risk of childhood infection from plasma-derived clotting factor concentrates.A blood safety surveillance system in place since 1998 has found no new infections with hepatitis or HIV associated with these products among hemophilia patients.

Manufacturing and viral inactivation steps have made these products very safe. Some of the products used to treat bleeds in people with hemophilia are made from plasma from donated blood.Mortality rates and hospitalization rates for bleeding complications from hemophilia were 40% lower among people who received care in hemophilia treatment centers than among those who did not receive this care.About 70% of people with hemophilia in the United States receive multidisciplinary, comprehensive care in a network of federally funded hemophilia treatment centers.

ALL MY PATIENTS HAVE TALES CITY OF PUBLICATION TRIAL

A CDC-sponsored randomized clinical trial found that children who were treated on a regular basis to prevent bleeding had less evidence of joint damage by 6 years of age than did those who were treated only after a bleed had started.

Special blood tests are required to make the diagnosis.

For the one-third of babies born with hemophilia in families with no known history of hemophilia, the diagnosis is made when an unusual bleeding event occurs.

Sometimes prenatal genetic testing is done to diagnose hemophilia before birth. The diagnosis of hemophilia is made using a special blood test and most babies can be tested soon after birth.

In about two thirds of cases, there is a family history of hemophilia.

Based on CDC data, the median age at diagnosis is 36 months for people with mild hemophilia, 8 months for those with moderate hemophilia, and 1 month for those with severe hemophilia.

In the United States, most people with hemophilia are diagnosed at a very young age.